The detox gene (MTHFR) is rendered inactive when your diet is high in meat. Our diet should be 80% plant based or higher. You may have seen the acronym MTHFR, which stands for methylenetetrahydrofolate reductase. This is an enzyme that plays a role in processing the nutrient folic acid folate into a form the body can MTHFR Gene Mutations Explained: Symptoms, Risks & Testing Guide Common MTHFR Mutations and General Health MTHFR Mutation Treatment: Effective Approaches Guide An analysis of Methylenetetrahydrofolate reductase and Glutathione S transferase omega 1 genes as modifiers of the cerebral response to ischemia BMC Neurology Springer Nature Link