COM March 2009 Diagnosis UW School of Dentistry ORAL MELANOTIC MACULE (OMM) (Also called focal melanosis labial melanotic macule) A benign, localized, flat pigmented lesion of the oral mucosa Caused by a focal increase in melanin production Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Relative frequency of solitary melanocytic lesions of the oral mucosa Buchner 2004 Journal of Oral Pathology & Medicine Wiley Online Library Oral Melanoma: A Rare but Aggressive Oral Cancer Oral melanoma is a rare and highly aggressive malignant tumor that develops from melanocytes within the oral mucosa. It most commonly affects the Pathology Outlines Melanotic macule