Deficient Glutathione in the Pathophysiology of Mycotoxin Related Illness The Importance of Glutathione in Health and Healing Dr. Todd Maderis How Mycotoxins Trigger Mast Cell Activation and Brain Inflammation Mycotoxin induced depletion of intracellular glutathione and altered cytokine production in the human alveolar epithelial cell line A549 ScienceDirect Mold Illness is More Than a Chronic Inflammatory Response Syndrome Dr. Todd Maderis Mycotoxins are toxic. But they are only one of many stressors affecting the extracellular matrix. Ochratoxin, aflatoxins, and trichothecenes increase oxidative stress, deplete glutathione, disrupt mitochondria, and activate inflammatory signaling. That