Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Labial or Oral Melanotic Macule Benign, asymptomatic, and often underdiagnosed. Swipe to learn how to recognize, diagnose, and manage this simple yet important lesion! #thebasicdentist #rguhs #kuhs #tnmgrmu #OralPathology #MelanoticMacule #DentalFacts Pathology Outlines Melanotic macule Pathology Outlines Melanotic macule a Melanotic macule at the wetdry line of the lower lip. b Melanotic Download Scientific Diagram This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips.