Pyroglutamic Acidemia: An Underrecognized and Underdiagnosed Cause of High Anion Gap Metabolic Acidosis A Case Report and Revi Frontiers Glutathione and mitochondria Glutamyl Cycle Mitochondrial Glutathione in Cellular Redox Homeostasis and Disease Manifestation Glutathione is one of the most important molecules in detoxification. It drives Phase II conjugation and helps neutralize oxidative stress at the cellular level. But detoxification does not end with transformation. It Frontiers Glutathione: Pharmacological aspects and implications for clinical use in non alcoholic fatty liver disease