Melatonin and your sleep: Is it safe, what are the side effects and how does it work? Cultivating Health UC Davis Health The Long Lasting Effects of Melatonin on Your Body Is melatonin the answer to getting better sleep at night? Sleep experts caution against its long term use for insomnia. It might help you fall asleep in the short term, but it's better Melatonin Supplement Side Effects & Management Melatonin is a hormone that helps regulate the body's sleep wake cycle. Melatonin supplements may help with sleep timing, jet lag, or short term sleep Taking Too Much Melatonin Can I Take Melatonin Twice in One Night?