Glutathione deficiency can lead to a variety of signs and symptoms that affect your overall health. Here are some common signs to look out for: 1. **Increased Dark Spots** Glutathione Glutathione Synthetase Deficiency as a Cause of Hereditary Hemolytic Disease New England Journal of Medicine GGT (gamma glutamyltransferase): Diagnostic Significance and Clinical Insights Advanced Health Academy Molecular Medicine Reports Signs You Might Be Low on Glutathione in Athletic Performance and How IV Therapy Could Make a Difference Glutathione Depletion and Stalwart Anticancer Activity of Metallotherapeutics Inducing Programmed Cell Death: Opening a New Window for Cancer Therapy ACS Omega